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TIDES 2.0: Understanding Mental Health in Children with Cystic Fibrosis

This study, called TIDES 2.0, is looking at how common depression, anxiety, and behavior problems are in children with cystic fibrosis (CF). It also wants to see how these issues change over time. The study will follow children aged 18 months to 11 years who have CF. Researchers want to understand these mental health challenges better, especially since new CF treatments (CFTR modulator therapy) have become available and there's a growing concern about children's mental health. This study does not involve any specific treatments or drugs. The main goal is to find out how many children with CF experience these mental health problems between July 2024 and June 2028. The study is currently unclear about its recruitment status, and aims to enroll 600 participants.

Study design
This is an observational study, meaning researchers will watch and collect information without giving any specific treatments. It plans to include 600 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed to measure the prevalence of depression, anxiety, and behavioral problems between July 1, 2024, and June 30, 2028.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07048574

TIDES 2.0: Prevalence and Longitudinal Course of Depression, Anxiety, and Behavior Problems in Children With Cystic Fibrosis Under 12 Years of Age

Recruiting
Not specifiedAges 18–11Observational
State University of New York at Buffalo
~600 participants
Updated 2026-07-06 on ClinicalTrials.gov

At a glance

Recruiting sites
12 of 13 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Prevalence of depression, anxiety, and behavioral problems in children with cystic fibrosis
Measured over 07/01/2024 - 06/30/2028

Conditions

Cystic Fibrosis (CF)

Explore related trials

Cystic Fibrosis

Where it's being run

13 sites across 12 states
Florida2
California1
Colorado1
Indiana1
Massachusetts1
New York1
North Carolina1
Ohio1

Who to contact

Beth A Smith, MD
[email protected]
716-898-5940
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Exclusion

Unable or unwilling to participate in study procedures, or at Site PI discretion.

What this trial measures

  • Prevalence of depression, anxiety, and behavioral problems in children with cystic fibrosis07/01/2024 - 06/30/2028

    Estimate the national prevalence of depression, anxiety, and behavioral problems among children with cystic fibrosis aged 18 months through 11 years using the Behavior Assessment System for Children, Third Edition (BASC-3). At the baseline assessment (Time 1), parents complete the age-appropriate BASC-3 Parent Rating Scale, and children aged 8-11 years complete the BASC-3 Self-Report of Personality. BASC-3 classifications of emotional and behavioral symptoms will be used to estimate the prevalence of clinically significant symptoms.