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Exercise Timing and Blood Pressure Study

This study aims to understand how the time of day you exercise affects your blood pressure. Researchers are looking for young adults, aged 18-39, who have elevated blood pressure (120/80 mmHg or higher) but not full hypertension (below 140/90 mmHg). You cannot have a history of chronic or autoimmune diseases or sleep disorders. Participants will complete a single, 30-minute treadmill exercise session. The main goal is to see how your average daytime systolic blood pressure (the top number in a blood pressure reading) changes over 24 hours after exercising at different times of the day (morning, afternoon, or evening). The study is currently unclear on its recruitment status and plans to enroll 30 people.

Study design
This is an interventional study with no specified phase, planning to enroll 30 participants. It's a randomized crossover trial where each participant will exercise at different times of day.
What's involved
You will complete an assessment of your individual circadian rhythm, followed by three separate exercise sessions (morning, afternoon, and evening). Your blood pressure will be measured for 24 hours before and after each exercise session.
Compensation
Not stated in the trial record.
Follow-up
Your blood pressure will be assessed for 24 hours after each exercise session.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07049783

Examining the Circadian Timing Effects of the Hypotensive Response to Exercise

Recruiting
NAAges 18–39InterventionalTreatment
Freda Patterson
~30 participants
Updated 2025-08-17 on ClinicalTrials.gov
What's tested:Exercise

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Average daytime systolic blood pressure
Measured over 24-hours

Conditions

Young Adults
Hypertension
Post-Exercise Hypotension
Circadian Rhythm

Explore related trials

Hypertension

Where it's being run

1 sites across 1 states
Delaware1

Who to contact

Freda Patterson, PhD
[email protected]
302-831-6588
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

18-39 Years old
Resting blood pressure greater than or equal to 120/80 mmHg or less than 140/90 mmHg

Exclusion

Diagnosis or history of chronic or autoimmune disease (i.e., cardiovascular, metabolic, renal, endocrine, cancer)
Diagnosis or history of sleep disorder (i.e., obstructive sleep apnea, insomnia, restless leg syndrome)
Alcohol or drug dependence
Elevated risk for sleep disorders
Elevated risk for clinical depression
Normotensive (blood pressure less than 120/80 mmHg) or stage 2+ hypertension (blood pressure greater than or equal to 140/90 mmHg)
Body mass index less than 18.5 or greater than 35 kg/m2
Self-reported use of sleep medications/supplements (e.g., melatonin)
Self-reported use of medications influencing vascular physiology (e.g., antihypertensive medications, weight loss medications)
Highly physically active (greater than or equal to 300 minutes moderate-to-vigorous physical activity per week)
Currently pregnant or breastfeeding
Current tobacco use (greater than or equal to 1 cigarette in the past month)
Nighttime or rotating shift work within the last 3 months
Contraindications to aerobic exercise

What this trial measures

  • Average daytime systolic blood pressure24-hours

    Change in average daytime systolic blood pressure (post-exercise - pre-exercise)