Study on Simulated Burn Injury and Post-Exercise Recovery

This study is looking at how a simulated burn injury affects your body's ability to cool down after exercise in a hot environment. Researchers will apply an absorbent and impermeable material over 60% of your body to mimic a burn injury. The main goal is to see if your core body temperature recovers slower after exercise with this simulated injury compared to without it. They are looking for healthy volunteers between 18 and 65 years old. You cannot have known heart disease or other chronic medical conditions like cancer or diabetes. The study aims to enroll 28 participants, but its current status is unclear.

Study design
This interventional study plans to enroll 28 participants to understand the effects of simulated burn injury on post-exercise recovery.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Your core temperature will be measured from the start of the study until 60 minutes after you finish exercising.

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NCT07050264

The Effect of Simulated Burn Injury on Post Exercise Recovery in Hot Environments

Recruiting
NAAges 18–65InterventionalBasic science
University of Texas Southwestern Medical Center
~28 participants
Updated 2026-05-26 on ClinicalTrials.gov
What's tested:Simulated burn injury via application of absorbent and impermeable material over 60% of the body

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Core Temperature
Measured over From baseline to end of 60 minutes of recovery
Burn Injury
Body Temperature Regulation
Cardiovascular Physiology
1 sites across 1 states
Texas1
  • Craig G Crandall, PhD · PRINCIPAL_INVESTIGATOR · University of Texas Southwestern Medical Center

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Eligibility criteria

Inclusion

18 and 65 years of age
free of any significant underlying medical problems based upon a detailed medical history and physical exam, and normal resting electrocardiogram.

Exclusion

Known heart disease
other chronic medical conditions requiring regular medical therapy including cancer, diabetes, neurological diseases, and uncontrolled hypertension, etc. as well as serious abnormalities detected on routine screening.
Individuals who are pregnant, planning to become pregnant, or breastfeeding will be excluded, this will be confirmed in females using a urine pregnancy test.
Taking prescribed medications (such as beta blockers and non-dihydropyridine calcium channel blockers) or over-the-counter medications that have known influences on thermoregulatory response.
Current smokers, as well as individuals who regularly smoked within the past 3 years.
body mass index is ≥ 31 kg/m2.
  • Core TemperatureFrom baseline to end of 60 minutes of recovery