IMPACT-HCT Trial: Improving Goals of Care Conversations for Transplant Survivors
This study is looking at ways to help people who have had a hematopoietic cell transplant (HCT), also known as a bone marrow transplant, for blood cancers. We are testing if a website called Planning Advance Care Together (PACT) and/or patient navigation sessions can improve conversations about your future care goals. You might be able to join if you are 18 or older, had an HCT 1 to 5 years ago for a blood cancer, can speak and read English, and haven't completed all advance directives or had a goals of care conversation with your doctor. The study aims to see how many people enroll, complete the interventions, and finish the study assessments. The current recruitment status is unclear.
- Study design
- This study is interventional and will involve about 40 participants. You will be randomly assigned to one of four groups: PACT website plus patient navigation, patient navigation only, PACT website only, or standard care.
- What's involved
- You would interact with the PACT website over 4 weeks and/or have a 45-60 minute patient navigation session. You will also complete study assessments at baseline, and at 4 and 12 weeks after the intervention.
- Compensation
- Not stated in the trial record.
- Follow-up
- After completing the study intervention, you will be followed up at 4 and 12 weeks.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Patient Navigation and the Planning Advance Care Together Website to Improve Goals of Care Conversations in Hematopoietic Cell Transplant Survivors, IMPACT-HCT Trial
At a glance
Conditions
NCT07052630
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Fred Hutch/University of Washington Cancer Consortium
Seattle, Washingtonstudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Megan Shen, PhD · PRINCIPAL_INVESTIGATOR · Fred Hutch/University of Washington Cancer Consortium
Who to contact
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Inclusion
Exclusion
What this trial measures
- Feasibility (Rate of enrollment)At baseline
Descriptive statistics will be run, including means and standard deviations for continuous data and frequencies and proportions for categorical data. Feasibility cutoffs will be based on prior research and include \>= 50% of eligible patients will enroll in the study.
- Feasibility (Rate of completion of intervention components)At 12 weeks post intervention
For the patient navigation component, this means that patients participate in the single patient navigation session with a health coach. For the Planning Advance Care Together (PACT) condition, this means that patients set up an account with the PACT website and engage in at least accessing the website. Feasibility cutoffs will be based on prior research and include \>= 50% of enrolled patients will adhere to and complete assigned intervention components and study-related assessments.
- Feasibility (Rate of completion of study assessments)At baseline, and at 4 and 12 weeks post intervention
Descriptive statistics will be run, including means and standard deviations for continuous data and frequencies and proportions for categorical data. Feasibility cutoffs will be based on prior research and include \>= 50% of enrolled patients will adhere to and complete assigned intervention components and study-related assessments.
- Acceptability of interventionAt 4 weeks post intervention
Will be measured using the 4-item Acceptability of Intervention Measure. Items are rated on a 5-point Likert scale. Acceptability will be defined as a median score of \>= 4.
- Completion of advance directivesAt baseline, and at 4 and 12 weeks post intervention
Questions asking patients whether they have completed a do not resuscitate (DNR) order, living will or identified a health care proxy. This item is scored as having no advance directives (0) to all advance directives completed (3). In addition to the primary outcome of advance directives (0 to 3 score), investigators will also examine each outcome separately (e.g., yes/no to completing a health care proxy) as secondary measures.