This study is testing different ways to reduce asthma attacks for people aged 13 to 75 who have had asthma for at least a year and are currently using an inhaled corticosteroid (ICS). Researchers are comparing two main approaches: using an ICS like budesonide/formoterol or mometasone/formoterol as both a daily controller and a rescue inhaler, or taking azithromycin (an antibiotic) three times a week to prevent attacks. Some participants will also use both treatments, or receive standard care. All participants will use a web-based app to track their asthma symptoms weekly. The main goal is to see which approach best reduces the number of asthma attacks over up to 16 months. The study is currently unclear on its recruitment status and plans to enroll 3200 participants.

Study design

This is a four-arm, patient-level randomized trial involving 3200 participants. It compares different treatment strategies for asthma.

What's involved

You will use either an inhaled corticosteroid, azithromycin, or both, and answer 5 questions about your asthma each week using a web-based application.

Compensation

Not stated in the trial record.

Follow-up

Follow-up is for up to 16 months. Participants in azithromycin arms may be offered up to 12 additional months of follow-up after stopping azithromycin.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.