Study of BHV-1400 for IgA Nephropathy

This study is testing a treatment called BHV-1400 for people with IgA Nephropathy (IgAN), a kidney disease. The main goal is to see if BHV-1400 is safe and tolerable. Researchers will look at serious side effects, side effects that cause people to stop the study, and any deaths over a period of up to one year. They will also check for severe changes in lab test results. You can join if you are between 18 and 65 years old and have IgAN confirmed by a kidney biopsy. The study is currently unclear on its recruitment status and plans to enroll 20 participants.

Study design
This is an interventional study, meaning participants will receive a specific treatment. It plans to enroll 20 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for up to one year to monitor for side effects and lab abnormalities.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07054684

Study of BHV-1400 in IgA Nephropathy

Recruiting
PHASE1Ages 18–65InterventionalTreatment
Biohaven Therapeutics Ltd.
~20 participants
Updated 2026-06-23 on ClinicalTrials.gov
What's tested:BHV-1400

At a glance

Recruiting sites
15 of 15 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Number of participants with Serious AEs (SAEs), AEs leading to discontinuation, deaths
Measured over Up to 1 year
+1 more outcome measured
IgA Nephropathy
15 sites across 11 states
Florida4
Texas2
Connecticut1
Georgia1
Illinois1
Indiana1
Michigan1
Missouri1

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  • Number of participants with Serious AEs (SAEs), AEs leading to discontinuation, deathsUp to 1 year

    To assess the safety and tolerability of BHV-1400. This objective will be measured by assessing the number of unique subjects with SAEs, moderate or severe AEs, AEs leading to discontinuation or deaths

  • Number of participants with Grade 3-4 treatment-emergent laboratory abnormalitiesUp to 1 year

    To assess the safety and tolerability of BHV-1400. This objective will be measured by assessing the number of unique subjects with Grade 3 or 4 treatment-emergent laboratory abnormalities.