Sickle Cell Kidney Biorepository for Sickle Cell Disease and Trait

This study is creating a collection of blood and urine samples, called a biorepository, to better understand kidney disease in people with sickle cell disease (SCD) and sickle cell trait. Researchers want to learn how kidney disease starts and why it can be more severe in these conditions. This study is observational, meaning it collects information without testing new treatments. They plan to enroll up to 800 participants aged 18 to 65 who have sickle cell disease or sickle cell trait, and some control participants without these conditions. The main goals are to track changes in kidney function and albuminuria (a sign of kidney damage) over 10 years.

Study design
This is an observational study aiming to enroll up to 800 participants. It is not testing a specific drug or intervention.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants' kidney function and albuminuria will be measured over 10 years.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07064174

Sickle Cell Kidney Biorepository

Recruiting
Not specifiedAges 18–65Observational
University of Texas Southwestern Medical Center
~800 participants
Updated 2026-04-13 on ClinicalTrials.gov

At a glance

Recruiting sites
2 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Kidney function decline
Measured over 10 years
+1 more outcome measured
Sickle Cell Trait
Sickle Cell Disease (SCD)
Chronic Kidney Disease

NCT07064174

Where you'd take part

This study runs at 2 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Parkland Memorial Hospital

    Dallas, Texasstudy coordinator listed

    Recruiting

  • University of Texas Southwestern Medical Center

    Dallas, Texasstudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

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  • Kidney function decline10 years

    Mean change in the estimated glomerular filtration rate per year

  • Albuminuria10 years

    Mean change in the urine albumin-to-creatinine ratio per year