Observational Study of LEMS in Small Cell Lung Cancer
This study is looking at how often Lambert-Eaton Myasthenic Syndrome (LEMS) occurs in people who have small cell lung cancer (SCLC). LEMS is a rare disorder that affects the connection between nerves and muscles, causing muscle weakness. Researchers want to find out how many SCLC patients show signs of LEMS. You can join if you are an adult diagnosed with SCLC and are willing to share your medical information. The study will consider it a "success" if it can identify how many participants develop suspicious LEMS within one year. This is an observational study, meaning no specific treatments are being tested, and the current recruitment status is unclear.
- Study design
- This is a multi-center observational study planning to enroll 400 participants with small cell lung cancer.
- What's involved
- You would undergo a brief neurological evaluation and blood tests (VGCC antibody testing) every three months. If you show signs of LEMS and have positive antibody tests, your participation would end.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary goal is to measure suspicious LEMS at 1 year. If you meet the criteria for suspicious LEMS, your study participation will end at that point.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
A Study to Evaluate the Incidence of Clinically Suspicious Lambert-Eaton Myasthenic Syndrome (LEMS) in Subjects Diagnosed With Small Cell Lung Cancer (SCLC)
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Jacob Sands, MD · PRINCIPAL_INVESTIGATOR · Dana-Farber Cancer Institute
- Gilbert Youssef, MD · PRINCIPAL_INVESTIGATOR · Dana-Farber Cancer Institute
Who to contact
This trial hasn't published a contact. View it on ClinicalTrials.gov
What this trial measures
- Suspicious LEMS1 year
Incidence of clinically suspicious LEMS diagnosis