Evaluating Travoprost Implant for Glaucoma

This study is testing a new implant called Gen 2 Travoprost Intracameral Implant for people with glaucoma or ocular hypertension (high pressure in the eye). Researchers want to see how safe and effective this implant is compared to Timolol eye drops 0.5%. You might receive the Travoprost implant, Timolol eye drops, a sham procedure (a fake implant administration), or placebo eye drops (artificial tears). The main goal is to measure your eye pressure after 3 months to see if the implant works. To join, you must be at least 18 years old and have open-angle glaucoma or ocular hypertension in the eye being studied. You cannot have had certain eye surgeries before. The study plans to enroll 610 people, but its current status is unclear.

Study design
This is an interventional study comparing different treatments for glaucoma. It plans to enroll 610 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Your eye pressure will be measured at 3 months after treatment.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07075718

Phase 2/Phase 3 Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral Implant

Recruiting
PHASE2Ages 18+InterventionalTreatment
Glaukos Corporation
~610 participants
Updated 2026-03-02 on ClinicalTrials.gov
What's tested:Gen 2 Travoprost Intracameral ImplantTimolol eye drops 0.5%Sham ProcedurePlacebo eye drops

At a glance

Recruiting sites
3 of 3 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Intraocular pressure (IOP)
Measured over 3 months
Glaucoma
3 sites across 3 states
Colorado1
Oklahoma1
Texas1
  • Luis G. Vargas, MD · STUDY_CHAIR · Glaukos Corporation

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Eligibility criteria

Inclusion

Diagnosis of open-angle glaucoma or ocular hypertension in the study eye

Exclusion

Prior incisional glaucoma surgery in the study eye
Prior argon laser trabeculoplasty (ALT) in the study eye
Prior minimally invasive glaucoma (MIGS) surgery in the study eye
  • Intraocular pressure (IOP)3 months

    Change from baseline in diurnal IOP in the study eye at 8AM and 10AM at each of Day 11, Week 6, and Month 3 visits