Observational Study of Phage Treatment for NTM and Other Infections
This study is looking for adults aged 18 and older who have a bacterial or mycobacterial infection, especially Nontuberculous Mycobacterial (NTM) Lung Disease, that needs treatment. The goal is to understand how people respond to bacteriophage treatment (a type of therapy that uses viruses to kill bacteria). Researchers will collect blood and airway samples during follow-up visits from people who are considering or receiving bacteriophage treatment. They will compare samples from those who receive treatment with those who don't, to find out what changes in the body (like in the airway microbiome or immune response) are linked to improvement. The study plans to enroll 100 participants, but its current status is unclear.
- Study design
- This is an observational study, meaning researchers will watch and collect information from 100 participants. It is not specified if participants will be randomly assigned to groups.
- What's involved
- Blood and airway samples will be obtained during follow-up visits. The duration of these visits or the total number of visits is not specified.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for up to 2 years to measure biomarkers associated with clinical, radiographic, or culture improvement.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Biomarkers of Phage Treatment Response in NTM and Other Infections
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Doreen Addrizzo-Harris, MD, FCCP · PRINCIPAL_INVESTIGATOR · NYU Langone Health
Who to contact
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What this trial measures
- Biomarkers associated with clinical and/or radiographic improvement and/or culture improvementEnd of study (up to 2 years)
Improvement includes clearing of cultures or decrease in qualitative or resolution of signs and symptoms of infection after at least 6-8 weeks of bacteriophage therapy.