A Study of 68Ga-FAPI PET in Heart Failure
This study is looking at how well a special imaging test, called 68Ga-FAPI PET (positron emission tomography), works for people with a type of heart failure called heart failure with preserved ejection fraction (HFpEF). You would receive an injection of 68Ga-FAPI, which is a drug that helps doctors see certain things in your heart during the PET scan. Researchers want to see if this scan can measure changes in your heart at the beginning of the study and again after six months. To join, you need to be at least 30 years old, have HFpEF with specific symptoms, and meet other health criteria. The current status of this study is unclear, and it plans to enroll 35 participants.
- Study design
- This is an interventional study planning to enroll 35 participants. It is not specified if it is randomized or blinded.
- What's involved
- You would receive an injection of 68Ga-FAPI for a PET scan at the start of the study and again at 6 months.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for 6 months after the baseline measurements.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
A Study of 68Ga-Fibroblast Activation Protein Inhibitor (FAPI) Positron Emission Tomography in Heart Failure
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Omar Abou Ezzeddine, M.D, M.S · PRINCIPAL_INVESTIGATOR · Mayo Clinic
- Gregorio Tersalvi, M.D · PRINCIPAL_INVESTIGATOR · Mayo Clinic
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Myocardial 68Ga-FAPI (68Ga-Fibroblast Activation Protein Inhibitor) volumeBaseline and 6 Months
Myocardial 68Ga-FAPI volume will be determined by a PET (positron emission tomography) scan and measured in cm3
- Mean Standardized Uptake Value (SUVmean) and Max Standardized Uptake Value (SUVmax)Baseline and 6 Months
SUVmean and SUVmax will be determined by a PET (positron emission tomography) scan and measured as a dimensionless ratio
- Area of 68Ga-FAPI (68Ga-Fibroblast Activation Protein Inhibitor) uptakeBaseline and 6 Months
Area of 68Ga-FAPI will be determined by a PET (positron emission tomography) scan and measured as a % of polar map.
- 68Ga-FAPI target-to-background ratioBaseline and 6 Months
68Ga-FAPI target-to-background ratio will be determined by a PET (positron emission tomography) scan and measured as a dimensionless ratio.