Study Investigating Inspiratory Muscle Training with Cardiac Rehabilitation for Heart Failure
This study is looking at how inspiratory muscle training (IMT) using a PowerBreathe device, when combined with cardiac rehabilitation (CR), affects people with heart failure with reduced ejection fraction (HFrEF). We want to see if this combination improves how your muscles use blood flow during exercise and how much effort your breathing muscles need. You might be able to join if you are 18 or older, have HFrEF with mild to moderate symptoms (NYHA symptoms I-III), haven't been hospitalized in the last three months, and meet other health criteria. The study aims to enroll 70 participants. The current status of the study is unclear.
- Study design
- This interventional study plans to enroll 70 participants. It is comparing the effects of inspiratory muscle training with cardiac rehabilitation.
- What's involved
- You would use the PowerBreathe device for 12 weeks. Measurements of your muscle blood flow and breathing effort would be taken at the beginning and after 12 weeks.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your progress will be measured at 12 weeks after starting the intervention.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
A Study Investigating the Impact of IMT With CR On Exercise Responses In HF
At a glance
Conditions
NCT07086131
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Mayo Clinic in Rochester
Rochester, Minnesotano site contact published
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Joshua Smith, Ph.D. · PRINCIPAL_INVESTIGATOR · Mayo Clinic
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Change in locomotor muscle blood flow during exerciseBaseline, 12 weeks
Locomotor muscle blood flows will be measured via Doppler-ultrasound. This will be measured in mL/min.
- Change in respiratory muscle cost of breathing (VO2)Baseline, 12 weeks
Respiratory muscle cost of breathing is the oxygen uptake (VO2) to the respiratory muscles. Respiratory muscle VO2 is expressed as milliliters of oxygen per kilogram of body mass per minute.