A Study of Dotinurad Versus Allopurinol for Gout

This study is comparing two medications, dotinurad and allopurinol, to see which is more effective at lowering uric acid levels in people with gout. Gout is a type of arthritis caused by too much uric acid in the blood. Researchers want to see what percentage of participants achieve a serum uric acid (sUA) level below 6.0 mg/dL after 24 weeks. You might be able to join if you are between 18 and 75 years old, have had gout for at least one year, and have experienced at least two gout flares in the past 12 months. The current status of this study is unclear, but it plans to enroll about 500 participants.

Study design
This interventional study plans to enroll about 500 participants. It compares dotinurad to allopurinol.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint is measured at Week 24, indicating follow-up for at least 24 weeks.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07089875

A Study of Dotinurad Versus Allopurinol in Participants With Gout

Recruiting
PHASE3Ages 18–75InterventionalTreatment
Crystalys Therapeutics
~500 participants
Updated 2026-07-30 on ClinicalTrials.gov
What's tested:AllopurinolDotinurad

At a glance

Recruiting sites
90 of 103 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Percentage of Participants With an sUA Level <6.0 mg/dL at Week 24
Measured over Week 24
Gout
103 sites across 38 states
Texas13
Florida12
California11
Arizona5
Michigan5
Masovian Voivodeship4
Illinois3
Indiana3

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  • Percentage of Participants With an sUA Level <6.0 mg/dL at Week 24Week 24