A Study of Dotinurad Versus Allopurinol in Tophaceous Gout
This study is comparing two medications, dotinurad and allopurinol, for adults with tophaceous gout (a type of gout with visible lumps of uric acid crystals). Researchers want to see how well dotinurad lowers serum uric acid (sUA) levels compared to allopurinol after 24 weeks. To join, you must be between 18 and 75 years old, have had gout for at least one year, and have at least one measurable tophus on your hands, wrists, feet, or ankles. The study aims to enroll 250 participants, but its current recruitment status is unclear.
- Study design
- This interventional study is comparing dotinurad to allopurinol in 250 participants. The phase of the study is not specified.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary outcome is measured at Week 24, indicating follow-up for at least that duration.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
A Study of Dotinurad Versus Allopurinol in Tophaceous Gout
At a glance
Conditions
Where it's being run
89 sites across 28 statesWho to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Percentage of Participants with an sUA Level <5.0 mg/dL at Week 24Week 24