Project DEDUCE: Understanding Smoking and the Environment

This study, called Project DEDUCE, is looking at how your everyday environment affects cigarette smoking and can lead to relapse. Researchers want to understand this better by using digital tools on smartphones. All participants will receive transdermal nicotine replacement therapy (21 mg patches) to help them quit smoking. The study aims to find out the average number of days it takes for someone to start smoking again after quitting, measured over about 6.5 months. You may be able to join if you are 21 or older, smoke at least 10 cigarettes daily, have smoked for at least two years, intend to quit soon, and have a compatible smartphone. The current status of this study is unclear.

Study design
This interventional study plans to enroll 600 participants. All participants will receive transdermal nicotine replacement therapy (21 mg patches).
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed from their quit date to a 6-month follow-up, which is about 6.5 months.

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NCT07089901

Project DEDUCE: Digital Envirotyping to Develop Understanding of Cigarette Smoking and the Environment

Recruiting
PHASE4Ages 21+Interventional
Duke University
~600 participants
Updated 2026-07-23 on ClinicalTrials.gov
What's tested:transdermal nicotine replacement therapy

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Average number of days to smoking relapse
Measured over From quit date to 6-month follow-up (about 6.5 months)
Smoking
1 sites across 1 states
North Carolina1
  • Francis J. McClernon, PhD · PRINCIPAL_INVESTIGATOR · Duke University

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  • Average number of days to smoking relapseFrom quit date to 6-month follow-up (about 6.5 months)

    Participants will self-report smoking from quit date to the 6-month follow-up visit. Days to relapse will be defined as the first of seven consecutive days of smoking.