This study is comparing two devices, the EndoZip System and the OverStitch Endoscopic Suturing System (Apollo ESG), to see how well they help people with obesity lose weight and if they are safe. Both devices are used in an endoscopic procedure (a procedure using a thin, flexible tube with a camera) to change the stomach's size. You might be able to join if you are between 21 and 65 years old, have a BMI (Body Mass Index) between 30 and 50, and have tried other weight-loss methods without success. The study will measure how much total body weight you lose after 12 months. The current recruitment status is unclear, but the study plans to enroll up to 184 patients.

Study design

This is a randomized, blinded study with two groups, comparing the two devices. It will include up to 184 participants across multiple locations in the US and Europe.

What's involved

You would need to follow substantial behavioral and dietary changes, attend routine follow-up appointments, and complete laboratory tests for 12 months.

Compensation

Not stated in the trial record.

Follow-up

Participants will be followed for 12 months after the procedure to measure weight loss.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.