NCT07091396

Home Transcranial Direct Current Stimulation (tDCS) to Enhance Functional Recovery

Enrolling by Invitation
NAAges 18+InterventionalTreatment
Mayo Clinic
~55 participants
Updated 2026-01-30 on ClinicalTrials.gov
What's tested:Soterix® tDCS - Home treatmentCognitive-linguistic therapySoterix® tDCS - Lab treatment

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
For patients with post-stroke cognitive impairment--Stricker Learning Span and Symbols Test
Measured over Baseline, 3 weeks, 12 weeks, 15 weeks, 24 weeks
+1 more outcome measured
Stroke
Neurodegeneration
Brain Tumor
1 sites across 1 states
Minnesota1
  • Zafer Keser, MD · PRINCIPAL_INVESTIGATOR · Mayo Clinic

This trial hasn't published a contact. View it on ClinicalTrials.gov

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Eligibility criteria

Inclusion

At least 3 months after ischemic/hemorrhagic/anoxic stroke or 3 months after completion of cranial radiation or cranial surgery for treatment of primary or metastatic intracranial tumors or neurodegenerative conditions include, but are not limited to, primary progressive aphasia, corticobasal syndrome, progressive supranuclear palsy, Parkinson's disease, and Alzheimer's disease dementia.
Expected survival \>6 months
Functional impairment in the domains of language and/or cognition affecting quality of life determined by PI.
Have a legally authorized representative who is able to sign on their behalf in unable to consent for themselves (ex., individuals with aphasia).
Have a legally authorized representative who is able to sign on their behalf in unable to consent for themselves (ex., individuals with aphasia).

Exclusion

Pregnancy
Contraindication to tDCS, including metallic implanted objects.
Medical instability or inability to cooperate during the study as assessed by the treating physician to participate in the study.
Individuals with epilepsy
  • For patients with post-stroke cognitive impairment--Stricker Learning Span and Symbols TestBaseline, 3 weeks, 12 weeks, 15 weeks, 24 weeks

    The Stricker Learning Span (SLS) is a computer-adaptive digital word list memory test specifically designed for remote assessment and self-administration on a web-based multi-device platform (Mayo Test Drive).

  • For patients with post-stroke language impairment--Mayo-developed web-based languageBaseline, 3 weeks, 12 weeks, 15 weeks, 24 weeks

    The exam includes a standard protocol including sentence and word repetition, standard reading passage, vowel prolongation, speech alternating motion rates , sequential motion rates, picture description, naming, and animal fluency