Digital Genetic Testing Support for Young Adults with Cancer

This study is testing a new way to help young adults (ages 18-39) with cancer get genetic counseling and testing. Many young adults don't receive recommended genetic testing, which can help guide their care. This trial compares standard remote genetic services with an enhanced digital approach that includes a chatbot (Genetic Journey Chatbot) and digital education. The goal is to see if this enhanced digital model increases the number of people who receive genetic counseling and testing. Researchers will also look at how this new approach affects your knowledge, feelings, and future cancer screenings. You may be eligible if you are a young adult (18-39) with a cancer diagnosis.

Study design
This study plans to enroll 535 participants and compares two different approaches to genetic testing services. Participants will be randomly assigned to receive either standard remote genetic services or an enhanced digital model.
What's involved
If you join, you will have telehealth visits with a genetic counselor for education and to receive your results. You will also complete standard genetic testing and may get access to a chatbot and digital education.
Compensation
Not stated in the trial record.
Follow-up
The study will measure genetic counseling and testing uptake within 6 months of starting the study.

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NCT07091617

Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing in Young Adults With Cancer

Recruiting
NAAges 18+InterventionalHealth services
Alliance for Clinical Trials in Oncology
~535 participants
Updated 2026-08-05 on ClinicalTrials.gov
What's tested:TelemedicineGenetic TestingInternet-Based InterventionEducational InterventionPatient NavigationInterview

At a glance

Recruiting sites
278 of 280 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Uptake of genetic counseling
Measured over Within 6 months of baseline
+1 more outcome measured
Miscellaneous Neoplasm, Nos
Non-Neoplastic Condition, Nos
280 sites across 30 states
Michigan39
Illinois36
Minnesota21
Missouri21
Washington20
California15
Iowa15
North Carolina13
  • Angela Bradbury, MD · STUDY_CHAIR · Alliance for Clinical Trials in Oncology

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  • Uptake of genetic counselingWithin 6 months of baseline

    Defined as a binary outcome of whether an adolescent or young adult (AYA) underwent genetic counseling within 6 months post completion of the baseline survey. Will be compared between randomized arms using Cochran-Mantel-Haenszel (CMH) tests stratified by gender and a Bonferroni correction will be applied to control family-wise type I error.

  • Uptake of genetic testingWithin 6 months of baseline

    Defined as a binary outcome of whether an AYA underwent genetic testing within 6 months post completion of the baseline survey. Will be compared between randomized arms using CMH tests stratified by gender and a Bonferroni correction will be applied to control family-wise type I error.