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NCT07092995

Understanding Freezing of Gait Using Brain Signals and Virtual Reality

Enrolling by Invitation
NAAges 18+InterventionalBasic science
University of California, Los Angeles
~36 participants
Updated 2026-02-17 on ClinicalTrials.gov
What's tested:VR Freezing TaskDual TaskExternal Cueing

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
GPi gait-related spectral power
Measured over Day 1
+2 more outcomes measured

Conditions

Parkinson&Amp;#39;s Disease
Freezing of Gait
Freezing of Gait Symptoms in Parkinson&Amp;#39;s Disease

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NCT07092995

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • University of California, Los Angeles

    Los Angeles, Californiano site contact published

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Who to contact

This trial hasn't published a contact. View it on ClinicalTrials.gov

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Eligibility criteria

Inclusion

Patients meeting the MDS clinical diagnostic criteria for Parkinson's disease who are implanted with a Medtronic Percept DBS Device and SenSight Directional Leads in bilateral globus pallidus internus (GPi).
Able to walk unassisted indoors
Age 18 or older
Half of patients will have disabling freezing of gait as defined by freezing more than once per day by self-report on questions 1 \& 2 of the New Freezing of Gait Questionnaire
The other half of patients will not have freezing of gait as defined by self-report on question 1 of the New Freezing of Gait Questionnaire

Exclusion

Clinical diagnosis of dementia or severe cognitive impairment (MOCA \< 21)
History of stroke, traumatic brain injury, or other neurologic disorders besides Parkinson's disease
Comorbidities causing severe gait impairments
Unstable medical condition including cardio-vascular instability in the past 6 months
Unable or unwilling to comply with the testing protocol

What this trial measures

  • GPi gait-related spectral powerDay 1

    Globus pallidus internus (GPi) spectral power change during walking versus standing rest.

  • GPi event-related spectral powerDay 2

    Globus pallidus internus (GPi) spectral power changes from baseline time-locked to gait cycle events, freezing episodes, and voluntary stopping events

  • GPi gait-related spectral powerDay 3

    Globus pallidus internus (GPi) spectral power change during walking with versus without external cues.