Intranasal LAIV Mucosal Immunity Examination
This study is looking at how the immune system (your body's defense against illness) responds to a nasal spray flu vaccine called Live Attenuated Influenza Vaccine (LAIV). Researchers want to understand why this type of vaccine doesn't cause the same changes in the blood as shots do. They will study immune organs near the nose, like tonsils and adenoids, from people having surgery for sleep apnea. The goal is to see how your body's immune response changes after vaccination by comparing blood tests before and after. This study is for people aged 2 to 89 who are having tonsillectomy and adenoidectomy, and who haven't had this year's flu vaccine. The study is currently unclear on its recruitment status and plans to enroll 25 participants.
- Study design
- This is an interventional study, meaning participants will receive a specific treatment (the nasal spray vaccine). It plans to include 25 participants.
- What's involved
- You would receive the Live Attenuated Influenza Vaccine (LAIV) nasal spray. Blood tests will be taken before and after vaccination.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your immune response will be measured from enrollment up to 4 weeks after your surgery is completed.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Intranasal LAIV Mucosal Immunity Examination
At a glance
Conditions
Where it's being run
1 sites across 1 statesWho to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Serological outcomes will be compared before and after vaccination and between groups.From enrollment to 4 weeks after surgery is completed
The comparisons will specifically compare: Mean HAI Ab titers in serum and mucosal secretions