Observational Study of CS Reducer for Heart Failure with Preserved Ejection Fraction
This observational study is looking at how a CS reducer affects people with a type of heart failure called Heart Failure with Preserved Ejection Fraction (HFpEF) and Coronary Microvascular Dysfunction (CMD). These conditions mean your heart can't pump blood effectively, even though it looks like it's squeezing normally, and the small blood vessels in your heart aren't working right. The study aims to see if the CS reducer helps improve blood flow to the heart muscle. To join, you must be at least 18 years old and already enrolled in a separate study (IRB# 25-002292). The study will measure changes in blood flow to the heart muscle using a special MRI scan. The current status of this study is unclear, and it plans to include 25 participants.
- Study design
- This is an observational study, meaning researchers will watch and collect information without giving a specific treatment within this study. It plans to include 25 participants.
- What's involved
- You would undergo a 50-minute non-invasive stress perfusion Cardiovascular Magnetic Resonance (CMR) scan at the beginning and again at 6 months.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your heart's blood flow will be measured at the start of the study and again after 6 months.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
A Study Of CS Reducer For Symptomatic Heart Failure With HFpEF And CMD
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Claire Raphael, M.B.B.S., Ph.D. · PRINCIPAL_INVESTIGATOR · Mayo Clinic
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Change in endocardial:epicardial perfusion ratioBaseline, 6 Months
Endocardial:Epicardial Perfusion Ratio is a measure of myocardial blood flow and will be determined by Cardiovascular magnetic resonance (CMR)