This study aims to create a new way to measure opioid withdrawal, which is essential for improving how we manage opioid use disorder. Currently, there isn't a standard, FDA-approved tool to do this. This project will involve talking to people who have experienced opioid withdrawal to understand their symptoms. You might be able to join if you are 18 or older, have been diagnosed with opioid use disorder in the past year, speak English, and have experienced opioid withdrawal at least once in the last 30 days. You cannot participate if you are pregnant, breastfeeding, or have cognitive impairment. The study will be successful if it helps create a reliable and standardized assessment for opioid withdrawal symptoms.

Study design

This is an observational study with 30 participants. It uses a within-subject design, meaning each participant will complete two sessions.

What's involved

Participants will complete two sessions, comparing their responses to withdrawal questions after experiencing naloxone-precipitated withdrawal and after spontaneous withdrawal. Cognitive interviews will be conducted within 8 hours of each observation period ending.

Compensation

Not stated in the trial record.

Follow-up

Participants will be offered referrals to aftercare prior to study discharge. The primary endpoint, cognitive interviews, is measured within 8 hours of completing the withdrawal experience.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.