Visual Plasticity Following Brain Lesions Study

This study, called VIBRANT, is testing if a combination of transcranial random noise stimulation (tRNS) and perceptual learning-based training can help improve vision after brain damage. tRNS is a type of gentle electrical stimulation applied to specific areas of the brain. Perceptual learning-based training involves tasks like judging the direction of moving dots. You may be able to join if you are at least 18 years old and have vision loss due to a stroke, brain tumor, or traumatic brain injury. The study will measure changes in your ability to tell the direction of moving objects to see if the treatments are successful. The current recruitment status is unclear.

Study design
This is a double-blind, crossover study involving 30 participants. This means neither you nor the study staff will know which treatment you are receiving at a given time, and you will receive both the active stimulation and a sham (inactive) stimulation at different points.
What's involved
Your vision will be tested at the beginning and end of two different treatment periods, each lasting about a week.
Compensation
Not stated in the trial record.
Follow-up
Your vision will be assessed within a week after each treatment period.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07105358

Visual Plasticity Following Brain Lesions

Recruiting
NAAges 18+InterventionalTreatment
Georgetown University
~30 participants
Updated 2025-08-05 on ClinicalTrials.gov
What's tested:transcranial random noise stimulation (tRNS)Sham StimulationPerceptual learning-based training

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in Motion Discrimination Performance
Measured over Study visit 1 to 2 (within a week), and study visit 3 to 4 (within a week)
Visual Field Defect
Stroke
Hemianopia
Quadrantanopia
Cortical Blindness
Brain Tumor
Traumatic Brain Injury
Visual Field Defect, Peripheral
1 sites across 1 states
District of Columbia1

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  • Change in Motion Discrimination PerformanceStudy visit 1 to 2 (within a week), and study visit 3 to 4 (within a week)

    Change in accuracy on a computerized motion direction discrimination task programmed in the lab. The task assesses participants' ability to discriminate the direction of the peripherally presented moving dots at two locations (one within the blind field and the other at a mirror-symmetric location in the intact visual field). Accuracy is defined as the proportion of correct responses out of the total number of trials completed.