SLV-324 for Metastatic Solid Tumors

This study is testing a new treatment called SLV-324 for people with metastatic solid tumors (cancers that have spread from where they started). SLV-324 is given as an intravenous (IV) infusion, meaning it goes directly into your vein. Researchers want to find out how safe SLV-324 is, how your body handles it, and if it can help treat these cancers. This treatment works by targeting specific pathways in the body (targeted therapy) and by boosting the body's immune system (immunotherapy). You might be able to join if you are 18 or older, have a solid tumor that has spread, and your cancer has gotten worse after previous treatments. The main goal is to find the highest dose of SLV-324 that can be given safely. The current status of this study is unclear.

Study design
This is a Phase 1 study designed to find the right dose of SLV-324. It plans to include about 70 participants.
What's involved
SLV-324 will be given intravenously in repeated cycles. Treatment will continue until your disease gets worse or you stop treatment.
Compensation
Not stated in the trial record.
Follow-up
The main safety and dose information will be collected throughout treatment, which could be up to about 18 months.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07108114

SLV-324 Treatment of Metastatic Solid Tumors

Recruiting
PHASE1Ages 18+InterventionalTreatment
Solve Therapeutics
~70 participants
Updated 2026-02-23 on ClinicalTrials.gov
What's tested:SLV-324 intravenous (IV infusion)

At a glance

Recruiting sites
7 of 7 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
MTD or RDR
Measured over Through the duration of treatment, up to approximately 18 months
Metastatic Solid Tumors

NCT07108114

Where you'd take part

This study runs at 7 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Fox Chase Cancer Center

    Philadelphia, Pennsylvaniastudy coordinator listed

    Recruiting

  • Hoag Memorial Hospital Presbyterian

    Newport Beach, Californiastudy coordinator listed

    Recruiting

  • Mays Cancer Center; University of Texas Health San Antonio

    Houston, Texasstudy coordinator listed

    Recruiting

  • MD Anderson Cancer Center

    Houston, Texasstudy coordinator listed

    Recruiting

  • University Hospitals Cleveland Medical Center

    Cleveland, Ohiostudy coordinator listed

    Recruiting

  • University of Washington / Fred Hutchinson Cancer Center

    Seattle, Washingtonstudy coordinator listed

    Recruiting

  • Washington University

    St Louis, Missouristudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

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  • MTD or RDRThrough the duration of treatment, up to approximately 18 months

    Determination of the MTD (maximum tolerated dose) and/or RDR (recommended dosing regimen) for SLV-324