Dupilumab for Eosinophilic Esophagitis in Young Children

This study is looking at dupilumab, an experimental drug, for young children with active eosinophilic esophagitis (EoE), an allergic condition of the esophagus (food pipe) that can affect eating. The study aims to understand how safe, tolerable, and effective dupilumab is when given for 24 weeks. Researchers will also check for side effects, how much of the drug is in the blood, and if the body makes antibodies against the drug. Children aged 6 months to 6 years, weighing 5 to 15 kg, with active EoE and symptoms in the month before screening, may be able to join. The main goal is to track any serious side effects that happen during the first 24 weeks.

Study design
This is an interventional study planning to enroll 20 participants. The phase of the study is not specified.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The study will track serious side effects for up to 24 weeks after treatment begins.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07112378

A Study of Dupilumab in Small Children With an Allergic Condition of the Esophagus (Food Pipe): Eosinophilic Esophagitis

Recruiting
PHASE3Ages 6–6InterventionalTreatment
Regeneron Pharmaceuticals
~20 participants
Updated 2026-08-20 on ClinicalTrials.gov
What's tested:dupilumab

At a glance

Recruiting sites
13 of 13 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Incidence of treatment-emergent Serious Adverse Events (SAEs)
Measured over Up to 24 Weeks
Eosinophilic Esophagitis (EoE)
13 sites across 13 states
Arizona1
California1
Colorado1
Georgia1
Massachusetts1
New York1
North Carolina1
Pennsylvania1
  • Clinical Trial Management · STUDY_DIRECTOR · Regeneron Pharmaceuticals

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  • Incidence of treatment-emergent Serious Adverse Events (SAEs)Up to 24 Weeks