Bromelain for Post-surgery Facial Swelling
This study is looking at whether taking Bromelain, a dietary supplement, can help reduce facial swelling or how long swelling lasts after jaw surgery (orthognathic surgery). Researchers also want to understand how safe Bromelain is. You might be able to join if you are between 18 and 65 years old, are having jaw surgery, and do not have certain health conditions or allergies, like to pineapple. The study will measure changes in the amount and duration of your swelling to see if Bromelain is effective. The current status of this study is unclear, but it plans to enroll 200 participants.
- Study design
- This is an interventional study planning to enroll 200 participants. It is not specified if it is randomized or blinded.
- What's involved
- You would take one Bromelain tablet daily for 9 days (2 days before surgery and 7 days after). You would also keep a log of when you take the supplement and other medications, and attend clinic visits before and after surgery.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your swelling will be measured at 1, 2, and 4 weeks, and at 3 and 6 months after your surgery.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Bromelain for Post-surgery Facial Swelling
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Mohamed Bazina, DDS, MSD · PRINCIPAL_INVESTIGATOR · University of Kentucky
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Change in Volume of SwellingBaseline, and post intervention weeks 1, 2, 4, and months 3 and 6
Images will be obtained with the Vectra 3D imaging system to look at the volume of swelling in patients that undergo orthognathic surgery and measured in Cubic Centimeters. Will also have a heat map to visually show where swelling has increased or decreased since previously obtained imaging. All these images and measurements will be compared between the control and experimental groups.
- Duration of Swelling following Orthognathic SurgeryBaseline, and post intervention weeks 1, 2, 4, and months 3 and 6
Images will be obtained with the Vectra 3D imaging system to look at the volume of swelling in patients that underwent orthognathic surgery at multiple time periods. With comparisons of these multiple photos the duration of swelling can be assessed and compared to the average amount of time it takes swelling to go down in a patient not taking bromelain supplement.