Air Filtration Intervention for Asthma in Children
This study is testing if using an Austin Air Cleaner, a special air purifier, can reduce indoor air pollution and improve asthma in children. You might be able to join if you are 7-18 years old, have asthma symptoms, and live in lower-income housing in Northern Manhattan or the South Bronx, NYC. The researchers want to see if the air cleaner can reduce asthma attacks and improve lung function. They will measure your lung function (how well your lungs work) and airway inflammation (swelling in your breathing tubes). The study status is currently unclear.
- Study design
- This is an interventional study planning to enroll 55 participants. It will evaluate the effectiveness of a high-capacity HEPA filter air cleaner.
- What's involved
- You would have breathing tests (to measure exhaled nitric oxide and lung capacity) at different times over a year, and answer questionnaires about your asthma symptoms monthly for up to 12 months.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your lung function will be measured monthly for up to 1 year after the air cleaner is turned on, and asthma attacks will be tracked monthly for up to 12 months.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Cost Effective Air Filtration Intervention in Low-Income Housing to Reduce Asthma Morbidity
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Matthew S Perzanowski, PhD · PRINCIPAL_INVESTIGATOR · Columbia University
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Fractional Exhaled Nitric Oxide (FeNO)1 week before, immediately before, two weeks after, and one year after the air cleaner is turned on.
A portable fractional exhaled nitric oxide (FeNO) monitor will used to measure exhaled NO, a biomarker of airway inflammation. FeNO will be measured at four timepoints with respect to the time the air cleaner is turned on.
- Forced Expiratory Volume in 1 Second/ Forced Vital Capacity (FEV1/FVC) Ratio1 week before, immediately before, two weeks after, then once a month (up to 1 year) after the air cleaner is turned on.
Easy to use, pocket-size spirometers (MIR) will be delivered to the homes along with the initial delivery of equipment. Subjects will be thoroughly trained on how to perform a pulmonary function test (PFT). These spirometers connect via Bluetooth to an application previously installed on the subject's cell phone. PFT data will be downloaded onto Columbia University computers from the app and the results will be scored and validated by trained personnel under the supervision of a spirometry expert. FEV1/FVC measures the proportion of vital capacity expired in the first second of forced expiration to the full forced vital capacity (how much air can be exhaled). FEV1/FVC will be measured at 15 timepoints with respect to the time the air cleaner is turned on.
- Number of Attacks of WheezingOnce per month for up to 12 months after the air cleaner is turned on
The number of attacks of wheezing in the past 4 weeks will be reported.
- Number of Emergency Department (ED) Visits12 months after the air cleaner is turned on
Number of ED visits in the past year.