Observational Study of Cervical Cancer and Radiation Therapy Side Effects
This observational study aims to understand how radiation therapy (brachytherapy) affects cervical cancer at a biological level. Researchers want to see if brachytherapy changes the expression of tissue factor and other molecules in cervical cancer over time. You may be able to join if you are a woman aged 18 or older with cervical cancer and are already scheduled to receive brachytherapy. The study is looking for 20 participants. Success for this study means learning more about the molecular pathways in cervical cancer, which could lead to better treatments in the future. The current status of this study is unclear.
- Study design
- This is an observational study, meaning researchers will watch and collect information without giving new treatments. It plans to include 20 participants.
- What's involved
- You would provide blood and tissue samples (biopsies) from your cervical cancer or upper vagina before, during, and on the last day of your radiation therapy.
- Compensation
- Not stated in the trial record.
- Follow-up
- Tissue factor expression in tumors will be measured at 8 weeks after treatment.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Biological Drivers of Cervical Cancer and Side Effects From Radiation Therapy
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Jyoti Mayadev, MD · PRINCIPAL_INVESTIGATOR · University of California, San Diego
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Tissue factor expression in tumors8 weeks
Determine the temporal changes of tissue factor expression in the irradiated tumor immune microenvironment.