CYTALUX™ for Gastrointestinal Cancers

This study is testing a drug called CYTALUX™ (pafolacianine) along with a special camera that uses near-infrared (NIR) light. The goal is to see if CYTALUX™ can help doctors find gastrointestinal cancers like stomach, esophageal, and appendiceal cancers more easily during surgery. You might be able to join if you are 18 or older and have a diagnosis or strong suspicion of these types of cancer. The study will look at how well CYTALUX™ works over 12 months. The study is currently unclear about its recruitment status and plans to enroll 15 participants.

Study design
This is an open-label study, meaning both you and your doctors will know you are receiving CYTALUX™. It aims to enroll 15 adult participants.
What's involved
You will receive an injection of CYTALUX™ (pafolacianine) 1 to 24 hours before your standard surgery. During surgery, tumors will be checked with near-infrared imaging.
Compensation
Not stated in the trial record.
Follow-up
The study will assess the feasibility of CYTALUX™ over 12 months.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07124351

Intraoperative Imaging of Gastrointestinal Malignancies Using Pafolacianine (CYTALUX™)

Recruiting
PHASE4Ages 18+InterventionalDiagnostic
Cedars-Sinai Medical Center
~15 participants
Updated 2025-09-15 on ClinicalTrials.gov
What's tested:CYTALUX™ (pafolacianine)

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Feasibility of CYTALUX™ (pafolacianine) with near-infrared (NIR) fluorescent imaging
Measured over 12 months
Gastrointestinal Cancer
Gastric Cancer
Esophageal Cancer
Appendiceal Cancer
1 sites across 1 states
California1
  • Miguel Burch, MD · PRINCIPAL_INVESTIGATOR · Cedars-Sinai Medical Center

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  • Feasibility of CYTALUX™ (pafolacianine) with near-infrared (NIR) fluorescent imaging12 months

    Determine feasibility of using CYTALUX™ (pafolacianine) injection with near-infrared (NIR) fluorescent imaging for detecting any type adenocarcinoma (gastric, esophageal and appendiceal) in at least 70% of the patients.