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Toothpaste Tablets for Plaque and Gum Health

This study is looking at how well toothpaste tablets work compared to regular toothpaste in reducing plaque and improving gum health. Researchers will compare Denttabs toothpaste tablets to Colgate Cavity Protection toothpaste. You might be able to join if you are 18 years or older, have more than 20 teeth, and can follow study instructions. The main goal is to see changes in your plaque (a sticky film on teeth) and gingival (gum) health after six weeks. The current status of this study is unclear, and it plans to enroll 50 participants.

Study design
This study will involve 50 participants who will be randomly assigned to use either toothpaste tablets or conventional toothpaste. It is an interventional study, meaning participants will receive a specific treatment.
What's involved
You would use your assigned toothpaste for six weeks. Before and after this period, your plaque and gum health will be measured, and you'll complete a questionnaire.
Compensation
Not stated in the trial record.
Follow-up
Your plaque and gum health will be measured at six weeks after starting the study.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07124533

Effectiveness of Toothpaste Tablets on Plaque, Gingival Health and Caries Experiences

Not Yet Recruiting
PHASE3Ages 18+InterventionalPrevention
Loma Linda University
~50 participants
Updated 2026-07-10 on ClinicalTrials.gov
What's tested:Toothpaste TabletConventional Toothpaste

At a glance

Recruiting sites
0 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Plaque Index Score at Baseline
Measured over Change between baseline at visit 1 and visit 2, six weeks post baseline
+1 more outcome measured

Conditions

Gingival Inflammation
Dental Caries

Explore related trials

CariesGingivitis

Where it's being run

2 sites across 1 states
California2

Study leadership

  • So Ran Kwon, DDS, MS, PhD · PRINCIPAL_INVESTIGATOR · Loma Linda University

Who to contact

So Ran Kwon, DDS, MS, PhD
[email protected]
909 558 5118 · ext. 55118
Email the study team

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What this trial measures

  • Plaque Index Score at BaselineChange between baseline at visit 1 and visit 2, six weeks post baseline

    The quantity of plaque build-up is measured visually using the Quigley-Hein Plaque Index. The Plaque index can range from 0 to 5, with higher numbers indicating more plaque build-up.

  • Gingival Index Score at BaselineChange between baseline at visit 1 and visit 2, six weeks post baseline

    The severity of gingival inflammation is measured visually using the Loe-Silness Gingival Index. Gingival index can range from 0 to 3, with higher numbers indicating more gingival inflammation.