Virtual Reality for Chronic Pain and Opioid Misuse

This study is testing a new way to help people with chronic pain and opioid misuse or opioid use disorder (OM/OUD) using virtual reality (VR). The intervention involves a single 45-minute VR session using a Meta Quest 3 headset. This session includes an AI (artificial intelligence) check-in, pain coping skills training, and a stress reduction exercise. The main goal is to see if this VR approach is practical and acceptable to patients. You might be able to join if you are 18 or older, have chronic pain of at least moderate intensity, and have an opioid misuse or opioid use disorder diagnosis. This study plans to enroll 15 participants.

Study design
This is an interventional study, meaning participants will receive a specific intervention. It is a small pilot study with a planned enrollment of 15 participants.
What's involved
You would participate in a single 45-minute virtual reality session. You would also complete a survey about your VR experience up to one hour after the session.
Compensation
Not stated in the trial record.
Follow-up
The study measures feasibility, such as recruitment rate and completion, over approximately 6 months. Your VR experience will be assessed up to one hour after your session.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07124598

Virtual Intelligence for Transformative Lifestyle Solutions in Pain

Completed
NAAges 18+InterventionalSupportive care
Montefiore Medical Center
~15 participants
Updated 2026-08-11 on ClinicalTrials.gov
What's tested:VR Headset Device - Meta Quest 3

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Feasibility - Recruitment Rate
Measured over Approximately 6 months
+5 more outcomes measured
Chronic Pain
1 sites across 1 states
New York1
  • Moorice A Caparo, MD · PRINCIPAL_INVESTIGATOR · Montefiore Medical Center

This trial hasn't published a contact. View it on ClinicalTrials.gov

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Eligibility criteria

Inclusion

Patients with opioid misuse or International Classification of Diseases 10th revision (ICD-10) diagnosis of opioid use disorder
Patients with Chronic pain of at least moderate intensity (\>4 Pain Intensity Score) with no pain medication changes in 14 days
Ability to understand written/spoken instruction and provide informed consent in English
Ability and willingness to participate in all components of the study

Exclusion

History of severe motion sickness, cybersickness, or conditions that could make participation in VR hazardous or cause adverse effects
Conditions that could prevent proper use of VR headset (such as vision problems that cannot be corrected by contact lenses or glasses that fit in VR, Significant hearing impairments that cannot be corrected by a hearing device)
History of seizures or seizure disorder
Acute exacerbation of psychiatric conditions such as self-injurious behaviors or suicidal risk that preclude the ability to participate in the study
  • Feasibility - Recruitment RateApproximately 6 months

    Feasibility of the intervention will be assessed by tracking and determining the recruitment rate for the study. For purposes of this study recruitment rate will be defined as the number/percentage of participants who are consented, screened, and enrolled over the 6-month timeframe will be summarized and reported.

  • Feasibility - CompletionApproximately 6 months

    Feasibility of the intervention will also be assessed by the number/percentage of participants who are able to successfully complete all three AI-guided, VR sessions. The number/percentage of participants that complete all three sessions will be summarized and reported using basic descriptive statistics.

  • Feasibility - Virtual Reality Experience and Feasibility Survey (VREFS)Up to 1 hour following completion of ~ 45-minute VR session

    Feasibility of the intervention as assessed by VREFS will also be determined. The VREFS is a comprehensive feasibility tool which measures feasibility across 7 distinct dimensions: Core Therapeutic Alliance (6 items); Cultural Competence \& Identity (5 items); Continuity \& Future Use (3 items); Privacy \& Trust (8 items); Medical Trust (3 items); Usability (11 items); and Overall Experience (6 items). The survey also consists of 4 additional items and 6 avatar-specific items. Participants are asked to evaluate and rate each statement on a 7-point scale ranging from 1 ("Strongly disagree") to 7 ("Strongly agree") such that higher scores are associated with a more favorable assessment of the intervention and study. Results will be summarized and reported using basic descriptive statistics.

  • Acceptability - Acceptability of Intervention Measure (AIM)Up to 1 hour following completion of ~ 45-minute VR session

    Acceptability of the intervention will be evaluated using AIM. AIM consists of 4 statements which asks participants to rate the acceptability of the intervention measures on a 5-point scale ranging from 1 ("Completely disagree") to 5 ("Completely agree") for an overall possible scoring range of 4-20, with higher scores being indicative of greater acceptability of the measures. Results will be summarized using basic descriptive statistics.

  • Satisfaction - ChangeUp to 1 hour following completion of ~ 45-minute VR session

    Satisfaction will be measured and assessed using the Patient's Global Impression of Change Scale (PGIC) questionnaire completed following the VR intervention. Participants will be asked to respond to the following query, "Since beginning treatment at this clinic, how would you describe the change (if any) in Activity, Limitations, Symptoms, Emotions and Overall Quality of Life, related to your painful condition? (tick only 1 box)" on a 7-point Likert scale ranging from 1 - "No change (or condition is worse)" to 7 "A great deal better, and a considerable improvement that has made all the difference" such that higher scores are associated with improved global impression of change. Results will be summarized using basic descriptive statistics.

  • Satisfaction - Degree of ChangeUp to 1 hour following completion of ~ 45-minute VR session

    Satisfaction will be also measured and assessed using the following question derived from the PGIC questionnaire: "In a similar way, please circle the number below that matches your degree of change since beginning care at this clinic." Participants will be asked to rate the degree of change on an 11-point scale ranging from 0 ("Much better") to 10 ("Much worse") such that lower scores are associated with a worsened degree of change. Results will be summarized using basic descriptive statistics.