Ketones for Opioid Craving Study
This study is looking at whether a ketone supplement can help reduce opioid cravings and withdrawal symptoms for adults with opioid use disorder (OUD) who are starting inpatient withdrawal treatment. Researchers will compare the ketone supplement to a placebo (an inactive drink) to see if it helps with cravings, low mood, and pain. You might be able to join if you are 18-75 years old, have OUD, and are admitted for opioid withdrawal management at Caron Treatment Center. The main goal is to see if the ketone supplement can lower your craving for opioids. The study is currently unclear about its status and plans to enroll 50 participants.
- Study design
- This is an interventional study comparing a ketone supplement to a placebo in 50 participants. It is designed to see if the supplement can reduce opioid craving and withdrawal symptoms.
- What's involved
- You would receive either the ketone supplement or a placebo drink three times daily for seven days. You would also complete assessments for mood, pain tolerance, and opioid withdrawal.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your craving levels will be measured at the beginning of the study and again on day 7.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Ketones for Opioid Craving
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Peter Manza, PhD · PRINCIPAL_INVESTIGATOR · University of Maryland, Baltimore
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Tonic Craving (FORCAST) total scoresCollected at baseline, and day 7
Faceted Opioid Research Craving Assessment for Substance use Treatment (FORCAST) (Opioid Craving): A 26-item assessment of tonic craving that the person reports having felt over the prior one or two weeks. Participants indicate how much they disagree or agree with each statement on a scale that ranges from 0-6, with 0 representing "strongly disagree", 3 representing "neither agree nor disagree", and 6 representing "strongly agree". Higher scores indicate higher levels of craving. The minimum score is 0, and the maximum scores for each of the subscales are as follows: Preoccupation: 24 Negative Reinforcement: 30 Positive Reinforcement: 24 Motivation: 30 Lack of control: 24 Uneasiness: 24 Maximum total score for all subscales = 156