This study is looking at people with heart failure and a leaky heart valve (functional mitral regurgitation) who are having a procedure called TEER with the MitraClip device. Researchers want to understand if the amount of scarring in the heart muscle, seen on a special MRI scan (Cardiac MRI), can predict how well the heart recovers after the MitraClip procedure. You could join if you are an adult with heart failure, reduced pumping ability of your heart (ejection fraction less than 50%), and are scheduled to receive a MitraClip. The study will measure success by looking at changes in your heart's pumping ability over 6 months. The current recruitment status is unclear.

Study design

This is an observational study involving up to 125 participants across multiple centers. It will look at how your heart changes after treatment without assigning you to a specific treatment.

What's involved

You would have a Cardiac MRI and complete a quality-of-life questionnaire before your MitraClip procedure. Six months later, you would repeat the questionnaire, Cardiac MRI, and have an echocardiogram. Your health records will be reviewed yearly for up to three years.

Compensation

Not stated in the trial record.

Follow-up

Participants will be followed for 6 months for the primary measurements, and clinical outcomes will be tracked through health records and phone contact for up to three years after the MitraClip procedure.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.