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Evaluating Neuromuscular Function in Children During Surgery with TetraGraph

This study is looking at how a device called TetraGraph works to measure muscle function in children during surgery. The TetraGraph is a portable device that uses electrical signals (EMG) to monitor how well muscles are working. Researchers want to see if there are differences in muscle function between infants (under 3 months old) and older children (12 years and above) during surgery. The main goal is to measure the strength of muscle signals (amplitude) during the first 30 minutes of surgery. You might be able to join if you are between 28 days and 25 years old, are having surgery with a specific type of anesthesia, and don't have certain nerve conditions. The current recruitment status is unclear.

Study design
This is an interventional study planning to enroll 100 participants. It is designed to evaluate the TetraGraph device.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be monitored for muscle signal strength during the first 30 minutes of surgery.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07133412

An Evaluation of the Neuromuscular Junction in Neonates Using the TetraGraph

Not Yet Recruiting
NAAges 28–25InterventionalDiagnostic
Joseph D. Tobias
~100 participants
Updated 2026-04-03 on ClinicalTrials.gov
What's tested:TetraGraph

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Amplitude
Measured over First 30 minutes of surgery

Conditions

Surgery

Explore related trials

Surgical Procedure

Where it's being run

1 sites across 1 states
Ohio1

Study leadership

  • Joseph D Tobias, MD · PRINCIPAL_INVESTIGATOR · Nationwide Children's Hospital

Who to contact

Julie Rice-Weimer, RN
[email protected]
614-355-3142
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

ASA 1-3 patients
Aged 28 days - 3 months or ≥ 12 years
Undergoing a surgical procedure with a volatile-agent based anesthetic that does not require administration of a neuromuscular blocking agent

Exclusion

Patients with history of a peripheral neurologic or neuropathic disorder
Patients in whom the upper extremity cannot be used for TOF monitoring
Patients undergoing a surgical procedure in which neuromuscular blockade is required
Edematous patients
Patients receiving total intravenous anesthesia (TIVA)

What this trial measures

  • AmplitudeFirst 30 minutes of surgery

    Average amplitude of the evoked response of the muscles.