AvertD Post-Approval Study for Opioid Use Disorder

This study is looking at a genetic test called AvertD. This test helps determine the likelihood of developing Opioid Use Disorder (OUD) before someone is prescribed opioids. The study wants to see how well AvertD works (its sensitivity and specificity) over five years. You might be able to join if you are 18 or older, have not received an opioid prescription before, and are being considered for your first oral opioid prescription within 4 to 30 days. You must also be willing to complete yearly assessments for five years and have AvertD prescribed as part of your care. The current recruitment status is unclear.

Study design
This is an observational study planning to enroll 4000 participants. It is not specified if it is randomized or blinded.
What's involved
You would need to complete yearly assessments for 5 years. You must also have AvertD prescribed as part of your care.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 5 years to measure the sensitivity and specificity of AvertD.

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NCT07135323

AvertD Post-Approval Study

Recruiting
Not specifiedAges 18+Observational
Prescient Medicine Holdings, Inc.
~4,000 participants
Updated 2025-08-22 on ClinicalTrials.gov
What's tested:Opioid Used Disorder Risk Assessment

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Sensitivity and Specificity of AvertD
Measured over Measured over 5 years
Opioid Use Disorder
1 sites across 1 states
Indiana1

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Eligibility criteria

Inclusion

≥18 years of age
Prior to first opioid prescription
Being considered for first oral opioid prescription (4-30 days)
Prescribed AvertD as part of care
Willing and able to complete yearly assessments for 5 years
Signed informed consent

Exclusion

Planned opioid prescription \<4 or \>30 days
Any condition making participation unsafe or infeasible per investigator judgment
  • Sensitivity and Specificity of AvertDMeasured over 5 years

    Comparison of Averted results to diagnosis of Opioid Used Disorder from M.I.N.I. tool