Detecting Pulmonary Hypertension with the Eko CORE 500 Digital Stethoscope

This observational study is looking at whether the Eko CORE 500 digital stethoscope can help screen for pulmonary hypertension (PH), a condition where blood pressure in the arteries leading to the lungs is too high. Researchers will use the Eko CORE 500 to record heart sounds (phonocardiogram or PCG) and electrical activity of the heart (electrocardiogram or ECG) from adults aged 18 and older. You could join if you are already scheduled for a heart ultrasound (transthoracic echocardiogram or TTE) or a right heart catheterization (RHC) within seven days of the study visit. The main goal is to see if these recordings can accurately detect PH. The study aims to enroll 1513 participants, but its current status is unclear.

Study design
This is an observational study, meaning participants will not receive an experimental treatment. It aims to enroll 1513 adults.
What's involved
You would have one study visit lasting about 20 minutes. During this visit, staff will take at least four 15-second recordings of your heart using the Eko CORE 500 stethoscope.
Compensation
Not stated in the trial record.
Follow-up
The primary outcome is measured at study completion, up to 12 months, with reference measurements taken within 7 days of the study recording visit.

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NCT07136623

Detecting Pulmonary Hypertension With the Eko CORE 500 Digital Stethoscope

Recruiting
Not specifiedAges 18+Observational
Eko Devices, Inc.
~1,513 participants
Updated 2026-08-24 on ClinicalTrials.gov
What's tested:Eko CORE 500 phonocardiogram (PCG) recordingEko CORE 500 three-lead electrocardiogram (ECG) recording

At a glance

Recruiting sites
1 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Area under the receiver operating characteristic (ROC) curve (AUC) for pulmonary hypertension (PH) detection
Measured over Study completion (up to 12 months); reference within ±7 days.
Pulmnary Hypertension
2 sites across 2 states
California1
North Carolina1
  • Michael Troy, MD · PRINCIPAL_INVESTIGATOR · University of California, Los Angeles

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  • Area under the receiver operating characteristic (ROC) curve (AUC) for pulmonary hypertension (PH) detectionStudy completion (up to 12 months); reference within ±7 days.

    Description: Area under the receiver operating characteristic (ROC) curve (AUC) of the phonocardiogram (PCG) + electrocardiogram (ECG) algorithm for classifying pulmonary hypertension (PH) vs. non-PH using probability outputs; reference is transthoracic echocardiography (TTE) and/or right heart catheterization (RHC) within ±7 days. 95% confidence intervals (CIs) reported.