The AHA Oneida Study: Cultural Nutrition for Stroke Risk and Cognitive Health

This study, called The AHA Oneida Study, is looking at whether a cultural nutrition program can help reduce the risk of stroke and improve thinking skills in members of the Oneida Nation. It also aims to see how school programs teaching about healthy Native American food choices can improve health. Participants will receive health wellness coaching focused on cultural nutrition. To understand the effects, you would have a carotid ultrasound (an imaging test of blood vessels in your neck), cognitive testing (to check thinking skills), blood work, and a health assessment. The study hopes to see changes in stroke and mini-stroke (TIA) rates, and improvements in blood pressure. This study is for Oneida Nation members aged 7 to 85 who receive healthcare through the Oneida Comprehensive Health Division. The current status of this study is unclear.

Study design
This is an interventional study with a planned enrollment of 95 participants. It is exploring the effects of health wellness coaching and school-age nutritional education programs.
What's involved
You can expect to be in the study for 1 year. During this time, you will undergo a carotid ultrasound, cognitive testing, blood work, a health assessment, and receive health wellness coaching.
Compensation
Not stated in the trial record.
Follow-up
Changes in stroke, TIA, and blood pressure will be measured at baseline and again at 1 year.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07139132

The AHA Oneida Study

Recruiting
NAAges 7–85InterventionalPrevention
University of Wisconsin, Madison
~95 participants
Updated 2026-07-29 on ClinicalTrials.gov
What's tested:Health Wellness CoachingCarotid ultrasoundSchool-age nutritional education programCognitive TestingBlood work

At a glance

Recruiting sites
2 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in incidence of stroke and transient ischemic attack (TIA)
Measured over Baseline to 1 year
+7 more outcomes measured
Oneida Nation Members

NCT07139132

Where you'd take part

This study runs at 2 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • University of Wisconsin - Madison

    Madison, Wisconsinstudy coordinator listed

    Recruiting

  • Oneida Nation Reservation

    Oneida, Wisconsinno site contact published

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Robert Dempsey, MD · PRINCIPAL_INVESTIGATOR · University of Wisconsin, Madison

Opens a ready-to-send draft in your own email app — review before sending.

Want this trial checked against your situation?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

Age 7-85 years
Receiving healthcare though the Oneida Comprehensive Health Division

Exclusion

Not Native American
  • Change in incidence of stroke and transient ischemic attack (TIA)Baseline to 1 year

    Number of incidences of stroke or TIA during the study

  • Change in number of participants that meet American Heart Association (AHA) Simple Rules for Diastolic Blood Pressure.Baseline to 1 year

    The AHA's simple rules for diastolic blood pressure: Normal = Less than 80 mm Hg; Elevated = Less than 80 mm Hg with a systolic reading of 120-129 mm Hg; Stage 1 Hypertension = 80-89 mm Hg; Stage 2 Hypertension = 90 mm Hg or higher; Hypertensive Crisis = Higher than 120 mm Hg (along with a systolic reading higher than 180 mm Hg). Researchers will be reporting the change in number of participants with diastolic blood pressure \<90 mmHg.

  • Change in number of participants that meet AHA's Simple Rules for Systolic Blood Pressure.Baseline to 1 year

    The AHA uses these simple rules for systolic blood pressure (the top number): Normal is less than 120, Elevated is 120-129, Stage 1 Hypertension is 130-139, and Stage 2 Hypertension is 140 or higher. A systolic reading of 180 or higher indicates a hypertensive emergency. Researchers will be reporting the change in number of participants with systolic blood pressure \<140 mmHg.

  • Change in number of participants that meet AHA Simple Rules for Body Mass Index (BMI)Baseline to 1 year

    The AHA uses the following guidelines for Body Mass Index (BMI) in adults: Underweight = Less than 18.5; Normal Weight = Between 18.5 and 24.9; Overweight = Between 25 and 29.9; and, Obesity = 30 or higher. Researchers will be reporting any improvement in BMI.

  • Change in Montreal Cognitive Assessment (MoCA)Baseline to 1 year

    MoCA is scored out of a total of 30 points, with a score of 26 or above generally considered normal. The MoCA assesses various cognitive domains, including memory, visuospatial abilities, language, and executive functions. A lower score indicates potential cognitive impairment, with specific cutoffs for mild (19-23), moderate (10-18), and severe (0-9) impairment.

  • Change in NIH Toolbox ScoreBaseline to 1 year

    NIH Toolbox Cognition Battery consists of tests of multiple constructs to asses for cognitive, sensory, motor and emotional function

  • Change in Native American Acculturation Scale (NAAS)Baseline to 1 year

    NAAS is a 20-item questionnaire developed to assess the level of acculturation in Native Americans. It measures an individual's connection to both traditional Native American culture and mainstream American culture. Scores range from a low of 1, indicating low acculturation (or high Native American identity) to a high of 5, indicating high acculturation (or high mainstream American identity), with a score of 3 indicating "bicultural". The NAAS examines areas like identity, language, friendships, behaviors, attitudes, and generational/geographic background.

  • Change in knowledge of health through a structured culturally competent school education programs about nutritionBaseline to 1 year