This study is testing Phentolamine Ophthalmic Solution to see if it can improve vision in low light (mesopic visual acuity) for adults who have had keratorefractive surgery (like LASIK or PRK). Researchers also want to understand how safe Phentolamine Ophthalmic Solution is. You might be able to join if you are 18 or older, have had eye surgery more than 6 months ago, and experience night vision problems like glare or halos. The study will compare Phentolamine Ophthalmic Solution to a placebo (a drop with no medicine) to see if it improves your vision by at least 3 lines on an eye chart after 15 days. The study aims to enroll 200 participants, but its current status is unclear.

Study design

This is a randomized, placebo-controlled, and double-masked study, meaning neither you nor your doctor will know if you are receiving Phentolamine Ophthalmic Solution or the placebo. It plans to include 200 participants.

What's involved

You would use Phentolamine Ophthalmic Solution or a placebo drop once daily for 2 weeks. You would also visit the clinic once a week for 2 weeks for checkups and tests, and keep a daily diary of when you use the drops.

Compensation

Not stated in the trial record.

Follow-up

Your vision will be measured at Day 15, which is the primary endpoint for the study.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.