Synovial Fluid Withdrawal or PRP Injection for Acute ACL Tears
This study is looking at how removing excess fluid from your knee or injecting Platelet-Rich Plasma (PRP) affects swelling after a sudden tear of your anterior cruciate ligament (ACL). Researchers want to see if these procedures change the healing factors in your knee joint fluid. You might be able to join if you are between 18 and 50 years old, speak English, have a recently torn ACL with swelling, and are scheduled for ACL reconstruction surgery. The main goal is to measure the concentration of a specific cytokine (a protein that affects cells) called Collagen Type II, from when you join until your surgery. The study is currently unclear on its status and plans to enroll 99 participants.
- Study design
- This is an interventional study planning to enroll 99 participants. It will involve either withdrawing synovial fluid or injecting Platelet-Rich Plasma (PRP).
- What's involved
- You would have synovial fluid withdrawn at a preoperative clinic visit and again during surgery. You might also receive a Platelet-Rich Plasma (PRP) injection.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary endpoint, Collagen Type II Cytokine concentration, will be measured from enrollment up to the time of surgery.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Synovial Fluid Withdrawal or PRP Injection For Acute ACL Tears and Cytokines
At a glance
Conditions
NCT07142369
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Rush University Medical Center
Chicago, Illinoisno site contact published
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Adam Yanke, MD, PhD · PRINCIPAL_INVESTIGATOR · Associate Professor and Surgeon
Who to contact
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Inclusion
Exclusion
What this trial measures
- Concentration of Collagen Type II CytokineEnrollment up to surgery
Breakdown cytokine found in damaged cartilage