Reducing Infection in Lower Leg Skin Cancer Wounds
This study is investigating if using special antibacterial washes and ointments before skin cancer surgery on your lower leg can lower your risk of infection. Researchers want to see if applying Chlorhexidine gluconate (a skin wash) and Mupirocin 2% Ointment (an ointment for your nostrils) for five days before surgery helps prevent infections in wounds that are left open to heal. You could be eligible if you are at least 18 years old and are having skin cancer surgery on your lower leg where the wound will be left open. The main goal is to count how many participants get a surgical site infection within one month after their operation. The current status of this study is unclear.
- Study design
- This is an interventional study planning to enroll 848 participants. It compares a group receiving pre-surgery antibacterial treatment to a group receiving standard care.
- What's involved
- If you are in the treatment group, you would use a special skin wash daily and an ointment in your nostrils twice daily for 5 days before surgery. You would also send pictures of your wound at 2 and 4 weeks post-operation.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be monitored for signs of infection from the date of surgery to one month post-operation.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
The Effect of Bacterial Decolonization Before Skin Cancer Surgery on Infection Rate of Lower Extremity Wounds Left Open to Heal
At a glance
Conditions
NCT07142408
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
The Center for Dermatologic Surgery at Cooper University Health Care
Marlton, New Jerseystudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
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Inclusion
Exclusion
What this trial measures
- Number of Participants with Surgical Site Wound InfectionFrom date of surgery to 1-month post-operation
Signs of infection, including erythema, edema, drainage, and delayed healing, will be visually determined by study physicians with photographs of the surgical site collected from study participants. All patients will be followed up with a phone call at 1 month to monitor for any adverse events and additional signs of infection including pain, tenderness, warmth, and foul odor at the surgical site.