Brijjit® Device for Preventing Scars After Gender-Affirming Mastectomy

This study is testing a device called Brijjit® (BP100-6 and BP-75) to see if it can help prevent thick, raised scars (hypertrophic scars) after gender-affirming mastectomy. The Brijjit® device is a flexible, non-invasive tool that helps wounds heal. You could be eligible if you are at least 19 years old, having a double incision gender-affirming mastectomy, and can follow the study instructions and attend follow-up visits. The study will compare how well the Brijjit® device works on one side of your chest versus standard wound care on the other side. Researchers will check for hypertrophic scars at 6 weeks, 3 months, and 6 months after surgery. The goal is to see if Brijjit® can reduce scarring.

Study design
This is a randomized study involving 78 participants. Each participant will have the Brijjit® device on one side of their chest and standard care on the other side.
What's involved
You would need to apply the Brijjit® device after surgery and be willing to return for follow-up visits and study evaluations. You will be taught how to reapply the device at home if needed.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 6 months after surgery, with scar assessments at 6 weeks, 3 months, and 6 months.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07147166

Evaluating the Efficacy of Force Modulating Tissue Bridge Device in Preventing Hypertrophic Scars Following Gender-Affirming Mastectomy

Terminated
NAAges 19+InterventionalPrevention
University of California, San Francisco
~7 participants
Updated 2026-08-25 on ClinicalTrials.gov
What's tested:Brijjit® BP100-6 and BP-75Control: Standard of care and normal wound dressing

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Presence of Hypertrophic Scarring
Measured over 6 weeks postop
+11 more outcomes measured
Gender Dysphoria
Mastectomy
Hypertrophic Scar
1 sites across 1 states
California1
  • Esther A Kim, MD · PRINCIPAL_INVESTIGATOR · Study Principal Investigator

This trial hasn't published a contact. View it on ClinicalTrials.gov

  • Presence of Hypertrophic Scarring6 weeks postop

    Presence or Absence of HTS: HTS defined as a raised, firm fibrotic lesion that develops within the boundaries of surgical incision with a height cutoff of \>/= 1mm. Binary yes or no outcome.

  • Presence of Hypertrophic Scarring3 months postop

    Presence or Absence of HTS: HTS defined as a raised, firm fibrotic lesion that develops within the boundaries of surgical incision with a height cutoff of \>/= 1mm. Binary yes or no outcome.

  • Presence of Hypertrophic Scarring6 months postop

    Presence or Absence of HTS: HTS defined as a raised, firm fibrotic lesion that develops within the boundaries of surgical incision with a height cutoff of \>/= 1mm. Binary yes or no outcome.

  • Presence of Hypertrophic Scarring1 year postop

    Presence or Absence of HTS: HTS defined as a raised, firm fibrotic lesion that develops within the boundaries of surgical incision with a height cutoff of \>/= 1mm. Binary yes or no outcome.

  • Scar Characteristics6 weeks postop

    Qualitative description of scar: Scar color, pigmentation, texture, description (flat, thin, depressed, spread, raised)

  • Scar characteristics3 months postop

    Qualitative description of scar: Scar color, pigmentation, texture, description (flat, thin, depressed, spread, raised)

  • Scar Characteristics6 months postop

    Qualitative description of scar: Scar color, pigmentation, texture, description (flat, thin, depressed, spread, raised)

  • Scar Characteristics1 year postop

    Qualitative description of scar: Scar color, pigmentation, texture, description (flat, thin, depressed, spread, raised)

  • Scar Dimensions6 weeks postop

    Scar Scar length, width and thickness measured in cm. If HTS present: Length of HTS and incision ratio Location of HTS: Medial, Middle, or Lateral. Measured distance from sternum.

  • Scar Dimensions3 months postop

    Scar Scar length, width and thickness measured in cm. If HTS present: Length of HTS and incision ratio Location of HTS: Medial, Middle, or Lateral. Measured distance from sternum.

  • Scar Dimensions6 months postop

    Scar Scar length, width and thickness measured in cm. If HTS present: Length of HTS and incision ratio Location of HTS: Medial, Middle, or Lateral. Measured distance from sternum.

  • Scar Dimensions1 year postop

    Scar Scar length, width and thickness measured in cm. If HTS present: Length of HTS and incision ratio Location of HTS: Medial, Middle, or Lateral. Measured distance from sternum.