Understanding Blood Cancers: The TEMPUS AQUARIUS Study

The TEMPUS AQUARIUS Study is an observational study looking at blood cancers like Acute Myeloid Leukemia (AML) and Follicular Lymphoma (FL). This study doesn't involve new treatments; instead, it collects information from your routine care. Researchers will gather molecular (multi-omic) and clinical data from blood samples and leftover tissue or bone marrow during your regular doctor visits. The main goal is to understand how different biological markers in your body are connected to your real-world health outcomes over five years. You can join if you have a diagnosis of AML or FL and are willing to provide samples and consent. This study aims to improve our understanding of these cancers.

Study design
This is an observational study, meaning there are no interventions or treatments being tested. It plans to enroll 550 participants.
What's involved
You would provide blood samples and leftover tissue or bone marrow during your routine therapy and disease monitoring.
Compensation
Not stated in the trial record.
Follow-up
The study will assess outcomes over a period of 5 years.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07154823

A Longitudinal Multi-Center Molecular Biomarker Discovery Registry for Patients With Hematologic Malignancies

Recruiting
Not specifiedAges 0+Observational
Tempus AI
~550 participants
Updated 2026-07-21 on ClinicalTrials.gov
What's tested:None - Observational Study

At a glance

Recruiting sites
9 of 9 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
To assess biomarker landscape in the progression as well as baseline biospecimen samples and correlate with with real-world outcomes across multiple hematologic indications.
Measured over 5 years
Acute Myeloid Leukaemia (AML)
Follicular Lymphoma ( FL)
9 sites across 7 states
Ohio3
Iowa1
Maryland1
Missouri1
Nevada1
Pennsylvania1
South Dakota1
  • Michael Thompson, MD, PhD, FASCO · PRINCIPAL_INVESTIGATOR · Tempus AI

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  • To assess biomarker landscape in the progression as well as baseline biospecimen samples and correlate with with real-world outcomes across multiple hematologic indications.5 years

    The goal of this biomarker discovery registry is to assess DNA and RNA expression patterns and potential biomarkers in biospecimens collected at baseline and throughout treatment, with the goal of generating hypotheses about predictive markers for therapy selection, prognostic indicators, and potential mechanisms of resistance to standard-of-care therapies across multiple hematologic indications.