tDCS for Cancer-Related Fatigue and Weakness
This study is looking at whether a non-invasive brain stimulation called tDCS (transcranial direct current stimulation) can help reduce cancer-related fatigue and muscle weakness. Participants will receive either active tDCS or a sham (inactive) tDCS, along with elbow exercises. Researchers will measure how long you can perform a fatiguing task and your muscle strength to see if tDCS is effective. This study is for people aged 40-80 who have had cancer and are at least 6 months past their treatment. The study aims to enroll 75 participants, but its current recruitment status is unclear.
- Study design
- This is a pilot study using a randomized, double-blind crossover design, meaning you might receive the active treatment or a placebo, and neither you nor your doctors will know which. It plans to enroll 75 participants.
- What's involved
- You will participate in familiarization and testing sessions, which involve performing fatiguing muscle tasks with and without tDCS. The tDCS intervention lasts 20-30 minutes.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your fatigue task duration and muscle strength will be measured immediately after each stimulation session.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
tDCS for Cancer-Related Fatigue and Weakness
At a glance
Conditions
NCT07159100
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Kessler Foundation
West Orange, New Jerseyno site contact published
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Guang Yue, PhD · STUDY_DIRECTOR · Kessler Foundation
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Fatigue task durationImmediately post-intervention in each experimental session.
Duration (in seconds) that participants are able to maintain a submaximal isometric contraction (20-40% of maximal voluntary contraction) during a fatigue-inducing task, performed with and without transcranial direct current stimulation (tDCS).
- Muscle StrengthImmediately after each stimulation session
Peak muscle force (in Newtons) generated during a maximal voluntary contraction (MVC) of the arm muscles, assessed immediately before and after the fatiguing isometric contraction task. Comparison is made across active tDCS and sham conditions to determine the acute effects of neuromodulation on post-fatigue strength. Force is measured using a calibrated force sensor.