Lu-177 PSMA Therapy for Patients with Kidney or Bone Marrow Issues
This study is looking at how the treatment Lu-177 PSMA (also known as Pluvicto) works in patients who have prostate cancer and also have kidney problems or issues with their bone marrow. Researchers want to understand how much of the Lu-177 PSMA medicine is absorbed by tumors and other organs in these patients. You might be able to join if you are approved for Pluvicto therapy and have certain levels of kidney (renal) complications or compromised bone marrow function, which means your white blood cell (WBC) or platelet counts are outside a normal range. The main goal is to check the safety and any side effects (adverse events) of the treatment over about one year. The study is currently unclear on its recruitment status and plans to enroll 25 men.
- Study design
- This is an interventional study, meaning participants will receive a specific treatment. It aims to enroll 25 participants.
- What's involved
- You will receive Lu-177 PSMA through an IV and undergo SPECT/CT scans. The study will monitor your safety and side effects for about one year.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your safety and adverse events will be measured through study completion, which is an average of one year.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Evaluation of Targeted Radionuclide Therapy of Lu-177 PSMA in Patients With Compromised Renal and/or Bone Marrow Function
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Guofan Xu, MD · PRINCIPAL_INVESTIGATOR · M.D. Anderson Cancer Center
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
Do you actually qualify for this trial?
Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.
Exclusion
What this trial measures
- safety and adverse events (AEs).Through study completion; an average of 1 year
Incidence of Adverse Events, Graded According to National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTCAE) Version (v) 5.0