Understanding Quality of Life After Pancreatic Surgery

This observational study aims to understand how pancreatic surgery affects a patient's quality of life over time. Researchers will track changes in quality of life for up to 24 months after surgery using specific questionnaires (EORTC QLQ-C30 and EORTC QLQ-PAN26). The study is for people aged 18 and older who are having pancreatic surgery for conditions like pancreatic cancer, pancreatitis, or pancreatic cysts, and who can speak English. The goal is to gather more information about patients' experiences and satisfaction with their decision to have surgery, as this data is currently limited.

Study design
This is an observational study planning to enroll 250 participants. It will track participants' quality of life over time without any specific interventions being tested.
What's involved
You would complete quality of life questionnaires at several points: before surgery, immediately after surgery, and then at 3, 6, 12, 18, and 24 months after surgery.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for up to 24 months after their surgery to assess changes in quality of life.

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NCT07173257

PROMs After Pancreatectomy

Recruiting
Not specifiedAges 18+Observational
University of Arizona
~250 participants
Updated 2025-09-15 on ClinicalTrials.gov

At a glance

Recruiting sites
2 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change from Baseline in Quality of Life Measured by EORTC QLQ-C30 Scale up to 24 Months Post-Operatively
Measured over Baseline, Immediately Post-Op, 3, 6, 12, 18, and 24 months after surgery
+1 more outcome measured
Pancreas Neoplasms
Pancreatitis
Pancreatic Cyst
2 sites across 1 states
Arizona2

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Eligibility criteria

Inclusion

Patients \>18 years old who undergo pancreatic resection for any indication of any race, gender, or ethnicity who are fluent in English

Exclusion

\<18 years old
Deemed not to have capacity to consent.
  • Change from Baseline in Quality of Life Measured by EORTC QLQ-C30 Scale up to 24 Months Post-OperativelyBaseline, Immediately Post-Op, 3, 6, 12, 18, and 24 months after surgery

    The EORTC QLQ-C30 is a validated 30-item questionnaire assessing cancer-specific quality of life. The Global Health Status/QoL scale ranges from 0 to 100, with higher scores representing better quality of life. Unit of Measure: points Metric: Mean change from baseline Aggregation Method: Mean (SD) across participants

  • Change from Baseline in European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-Pancreatic Cancer Module (EORTC QLQ-PAN26) Subscale Scores up to 24 Months Post-OperativelyBaseline, Immediately Post-op, 3, 6, 12, 18, and 24 months after surgery

    The EORTC QLQ-PAN26 is a 26-item, disease-specific questionnaire designed for patients with pancreatic cancer. It is used alongside the core EORTC QLQ-C30. PAN26 assesses multiple domains, including pancreatic pain, digestive symptoms, altered bowel habits, hepatic symptoms, and emotional effects. Each subscale is linearly transformed to a score from 0 to 100. For symptom subscales, higher scores = worse symptoms. For functioning domains, higher scores = greater impairment. Unit of Measure: points (0-100) per subscale Metric: mean change from baseline Aggregation: mean (SD) across participants