Rocklatan Retinal Perfusion OCT Study for Glaucoma

This study is looking at how Rocklatan eye drops affect blood flow in the eyes of people with glaucoma. You might be able to join if you have open-angle glaucoma in both eyes, with specific vision and optic nerve changes. Researchers will give you Rocklatan eye drops to use nightly in one eye for up to 12 months. They will use two special cameras (Optical Coherence Tomography or OCT devices) to measure blood flow changes in both eyes. One of these cameras is approved by the FDA, and the other is still being tested. The main goal is to see if Rocklatan changes blood flow in the nerve fiber layer of your eye. The study is currently unclear on its recruitment status and plans to enroll 30 participants.

Study design
This is an interventional study, meaning participants will receive a specific treatment. It plans to enroll 30 participants.
What's involved
You would use Rocklatan eye drops nightly in one eye for up to 12 months. Both of your eyes will be imaged with two OCT devices to assess blood flow changes.
Compensation
Not stated in the trial record.
Follow-up
Blood flow in the nerve fiber layer will be measured from enrollment to the end of treatment, around 11-12 months.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07174401

Rocklatan Retinal Perfusion OCT Study

Not Yet Recruiting
PHASE4Ages 21+InterventionalTreatment
Oregon Health and Science University
~30 participants
Updated 2025-12-24 on ClinicalTrials.gov
What's tested:Rocklatan eye drops will be instilled nightly in one eye diagnosed with glaucoma for up to 12 months.Two optical coherence tomography (OCT) devices will be used to assess blood flow changes.

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Nerve Fiber Layer Plexus Capillary Density (NFLP CD)
Measured over From enrollment to end of treatment at 11-12 months
Glaucoma
1 sites across 1 states
Oregon1
  • David Huang, MD, PhD · PRINCIPAL_INVESTIGATOR · Oregon Health and Science University

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  • Nerve Fiber Layer Plexus Capillary Density (NFLP CD)From enrollment to end of treatment at 11-12 months

    The primary outcome measure will be change in the overall peripapillary NFLP CD measured at 6 months and 11-12 month endpoint visits compared to baseline values.