Adaptive Decision-making And Personalized Treatment for PTSD (ADAPT-PTSD)
This study is looking for veterans aged 18 or older who have Posttraumatic Stress Disorder (PTSD) and are not fully benefiting from their current treatment. You must also own a mobile device for a therapy app. Researchers want to see if trying different treatment strategies, like Modular Cognitive Processing Therapy (CPT), Modular Prolonged Exposure Therapy (PE), or standard CPT, can help more. They also want to find out if text message prompts encourage you to complete homework between sessions. The main goal is to see if these changes improve your PTSD symptoms, measured by a questionnaire called the PCL-5, at 10 weeks, 20 weeks, and 9 months.
- Study design
- This interventional study plans to enroll 302 participants. It uses a special design with multiple, sequential randomizations to different treatments.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your PTSD symptoms will be measured at 10 weeks, 20 weeks, and 9 months after starting treatment.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Adaptive Decision-making And Personalized Treatment for PTSD (ADAPT-PTSD)
At a glance
Conditions
Where it's being run
4 sites across 3 statesStudy leadership
- Stefanie LoSavio, PhD · PRINCIPAL_INVESTIGATOR · The University of Texas Health Science Center at San Antonio
- Rebecca Sripada, PhD · PRINCIPAL_INVESTIGATOR · VA Ann Arbor-506
Who to contact
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What this trial measures
- Posttraumatic Stress Disorder Checklist (PCL-5)10 weeks, 20 weeks and 9 months
The PCL-5 is a psychometrically valid measure and commonly used assessment of PTSD symptoms. A total score is calculated by adding up the ratings for each of the 20 items, which range from 0 to 4 (0=Not at all, 4=Extremely). Higher scores reflect more severe symptoms. A score below 31 generally suggests a sub-clinical range, while scores of 31 or above fall within the clinical range, indicating probable PTSD.