A Study of EDG-15400 in Healthy Adults

This study is looking for healthy adults to help us learn more about a medication called EDG-15400. We want to understand how safe EDG-15400 is, how well people tolerate it, and how much of it gets into the blood and urine after taking it. We'll also see if food affects how much EDG-15400 is absorbed and compare different forms of the medication (liquid versus tablet). Participants will receive either EDG-15400 or a placebo (an inactive substance) by mouth. The main goal is to check for any side effects. You can join if you are a healthy adult between 18 and 59 years old, with a BMI between 18.5 and 35, and weigh at least 55 kg.

Study design
This is an interventional study with 108 planned participants. Participants will receive either EDG-15400 or a placebo.
What's involved
Participants will receive single or multiple doses of EDG-15400 or placebo by mouth. The study involves monitoring for up to 25 days.
Compensation
Not stated in the trial record.
Follow-up
Participants will be monitored for safety for up to 25 days after treatment.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07177066

A Study of EDG-15400 in Healthy Adults

Completed
PHASE1Ages 18–59InterventionalBasic science
Edgewise Therapeutics, Inc.
~84 participants
Updated 2026-08-05 on ClinicalTrials.gov
What's tested:EDG-15400Placebo

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Safety: incidence of treatment-emergent adverse events
Measured over Up to 45 days of monitoring
Healthy Adults
1 sites across 1 states
Arizona1

This trial hasn't published a contact. View it on ClinicalTrials.gov

  • Safety: incidence of treatment-emergent adverse eventsUp to 45 days of monitoring

    To determine the safety and tolerability of EDG-15400 when administered as single and multiple ascending doses to healthy adults