NCT07186530
Offering HPV Self-Collection in Novel Healthcare Settings to Improve Uptake of Cervical Cancer Screening
Enrolling by Invitation
NAAges 30–63InterventionalScreeningMayo ClinicInvestigator-initiated
~500 participants
Updated 2026-06-09 on ClinicalTrials.gov
What's tested:Best PracticeCommunication InterventionElectronic Health Record ReviewHPV Self-CollectionStandard Follow-Up Care
At a glance
Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Cervical cancer screening test
Measured over Up to 6 months from trial enrollment
Conditions
Where it's being run
1 sites across 1 statesMinnesota1
Study leadership
- Kathy L. Maclaughlin, MD · PRINCIPAL_INVESTIGATOR · Mayo Clinic
Who to contact
This trial hasn't published a contact. View it on ClinicalTrials.gov
Do you actually qualify for this trial?
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Eligibility criteria
Inclusion
Women ages 30-63 years old receiving primary care with a provider at Mayo Clinic in Rochester and who self-identify as asymptomatic (i.e., no pelvic pain, abnormal vaginal bleeding or abnormal vaginal discharge)
Qualify for average risk cervical cancer screening per United States Preventive Services Task Force (USPSTF) guidelines but are overdue by \>= 1 year, including those who have never been screened
Must have an active Patient Online Services account (patient portal), approval for research contact status in portal/Epic and documentation of Minnesota (MN) research authorization, and health insurance coverage
Exclusion
History of hysterectomy
Cervical cancer
Cervical intraepithelial neoplasia (CIN) 2-3
In utero diethylstilbestrol (DES) exposure
HIV+
Use of chronic immunosuppressant medication
Known to be pregnant
Medicare-covered women are NOT eligible as Medicare does not cover primary HPV testing by clinician-collection or self-collection \[related to outdated Centers for Medicare \& Medicaid Services (CMS) cervical cancer screening coverage rules for Medicare that date back to 2015, 3 years before primary HPV screening was endorsed by USPSTF\]
What this trial measures
- Cervical cancer screening testUp to 6 months from trial enrollment
Assessed by the number of participants who complete cervical cancer screening collection from invitation to complete a self-collected vaginal swab for HPV testing at Mayo Clinic Express Care clinics compared to the number of participants who complete screening with a clinician-collected cervical swab or self-collected vaginal swab at a primary care office.