Telehealth Rehabilitation for Veterans with Chronic TBI

This study is looking at two types of telehealth (remote healthcare) training for Veterans aged 18-65 who have had a mild to moderate traumatic brain injury (TBI) more than six months ago and are experiencing cognitive (thinking) difficulties. The goal is to see if these trainings can help Veterans improve their daily functioning and reintegration into the community. One training, called GOALS TH, focuses on goal-oriented attention and self-regulation. The other, EDU TH, is an active control training that matches GOALS TH in terms of time commitment. Researchers will measure neurocognitive performance, specifically overall attention and executive function, at the beginning of the study, after 10 weeks of training, and again at 6 months. The study plans to enroll 80 participants, but its current status is unclear.

Study design
This interventional study plans to enroll 80 participants. It compares two behavioral telehealth interventions: GOALS TH and EDU TH.
What's involved
You would participate in ten 2-hour group telehealth sessions, three individual 1-hour telehealth sessions, and approximately 20 hours of home practice.
Compensation
Not stated in the trial record.
Follow-up
Your neurocognitive performance will be measured at the start, after 10 weeks of training, and again at 6 months.

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NCT07190365

Goal-oriented Telehealth Rehabilitation of Executive Functioning for Veterans With Chronic TBI

Recruiting
NAAges 18–65InterventionalTreatment
VA Office of Research and Development
~80 participants
Updated 2026-04-03 on ClinicalTrials.gov
What's tested:GOALS THEDU TH

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Neurocognitive performance -Overall Attention and Executive Function (AEF) Z score
Measured over Baseline, 10 week (post training), 6 month
Mild to Moderate Traumatic Brain Injury
Cognitive Rehabilitation
Veteran
1 sites across 1 states
California1
  • Tatjana Novakovic-Agopian, PhD · PRINCIPAL_INVESTIGATOR · VA Palo Alto Health Care System, Palo Alto, CA

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Eligibility criteria

Inclusion

History of mild to moderate TBI \> 6 months ago
Cognitive difficulties affecting daily functioning
Age 18-65
Veteran
At least 12th grade education or equivalent \* Interested in improving community reintegration

Exclusion

Amnesic/Severe memory problems
Active Substance Abuse/Dependence
Medical condition that may affect mental status/disrupt study participation
Active psychotropic medication changes
  • Neurocognitive performance -Overall Attention and Executive Function (AEF) Z scoreBaseline, 10 week (post training), 6 month

    Performance on neurocognitive composite measure of attention and executive function post intervention vs control training will be assessed with Overall Attention and Executive Function (AEF) domain composite Z Score (calculated as the average of z scores of following tests: Letter Number Sequencing, Auditory Consonant Trigrams, Digit Vigilance, Trails B, DKEFS Stroop Inhibition, DKEFS Stroop Inhibition-Switching, DKEFS Verbal Fluency Switching, DKEFS Visual Fluency Switching). AEF Z score range is -3 to +3; higher score = better outcome.